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CyFlow™ CD3 PE-DyLight™ 594
Application: | Flow cytometry |
Antigen: | CD3 |
Excitation Maximum: | 593 nm |
Format/Fluorochrome: | PE-DyLight™ 594 |
Isotype: | IgG2a |
Clone: | MEM-57 |
Alternative Name: | Leu4, T3 |
Laser: | Blue, Green, Yellow |
Clonality: | monoclonal |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Target Species: | Human |
Emission Maximum: | 618 nm |
Order number: | BJ520116 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA IV—WS Code T 96 Quantity 100 tests Volume 0.4 mL Immunogen... more
Product information "CyFlow™ CD3 PE-DyLight™ 594"
HLDA Workshop | HLDA IV—WS Code T 96 |
Quantity | 100 tests |
Volume | 0.4 mL |
Immunogen | Human thymocytes and T lymphocytes |
Background Information | CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3γ, CD3 δ, CD3ε and CD3ζ. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow CD3 PE-DyLight 594 (MEM-57) BJ520116 TDS RUO.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) BN544098 TDS ASR EN.pdf
Instruction for Use
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU DE DE.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU CZ CZ.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU CZ CZ.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU DE DE.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU DK DK.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU ES ES.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU FR FR.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU GB EN.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU GR EL.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU IT IT.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU NL NL.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU NO NO.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU PL PL.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU PT PT.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU RU RU.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU SE SV.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU SK SK.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) CU543153 IFU TR TR.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU DE DE.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU DK DK.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU ES ES.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU FR FR.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU GB EN.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU GR EL.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU IT IT.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU NL NL.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU NO NO.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU PL PL.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU PT PT.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU RU RU.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU SE SV.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU SK SK.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU TR TR.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU BG BG.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU HR HR.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU RO RO.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU SI SL.pdf
- CyFlow CD3 PE-DyLight 594 (UCHT1) AV916343 IFU RS SR.pdf
ECDoC
- CyFlow CD3 PE-DyLight 594 AV916343 ECDOC EN-DE.pdf
- CyFlow CD3 PE-DyLight 594 CU543153 ECDOC EN-DE.pdf
- CyFlow CD3 PE-DyLight 594 CU543153 EUDoC EN-DE.pdf
Certificate Of Analysis
- CyFlow CD3 PE-DyLight 594 BN544098 COA 902445.pdf
- CyFlow CD3 PE-DyLight 594 CU543153 COA 902287.pdf
- CyFlow CD3 PE-DyLight 594 CU543153 COA 903432.pdf
- CyFlow CD3 PE-DyLight 594 BN544098 COA 903432.pdf
- CyFlow CD3 PE-DyLight 594 AV916343 COA 904693.pdf
- CyFlow CD3 PE-DyLight 594 CU543153 COA 904693.pdf
- CyFlow CD3 PE-DyLight 594 BN544098 COA 904693.pdf
- CyFlow CD3 PE-DyLight 594 BN544098 COA 905076.pdf
- CyFlow CD3 PE-DyLight 594 AV916343 COA 906138.pdf
- CyFlow CD3 PE-DyLight 594 BN544098 COA 907180.pdf
- CyFlow CD3 PE-DyLight 594 BN544098 COA 907248.pdf
- CyFlow CD3 PE-Dylight 594 BN544098 COA 907681.pdf
- CyFlow CD3 PE-DyLight 594 AV916343 COA 907681.pdf
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