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CyFlow™ CD31 PerCP
| Application: | Flow cytometry |
| Format/Fluorochrome: | PerCP |
| Alternative Name: | endoCAM, PECA1, PECAM-1 |
| Antigen: | CD31 |
| Emission Maximum: | 678 nm |
| Excitation Maximum: | 482 to 490 nm |
| Isotype: | IgG1 |
| Clonality: | monoclonal |
| Laser: | Blue, Green |
| Field of Interest: | Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Target Species: | Human |
| Clone: | MEM-05 |
| Order number: | AS946732 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Leukocytes of a patient suffering from... more
Product information "CyFlow™ CD31 PerCP"
| Quantity | 100 tests |
| Volume | 1.0 mL |
| Immunogen | Leukocytes of a patient suffering from LGL-type leukemia |
| Background Information | CD31 (PECAM-1; platelet endothelial cell adhesion molecule-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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