CyFlow™ CD45R FITC

Antigen:	CD45R
Clone:	RA3-6B2
Application:	Flow cytometry
Format/Fluorochrome:	FITC
Laser:	Blue
Target Species:	Cat, Human, Mouse
Field of Interest:	Immunophenotyping, Phosphorylation
Species of Origin:	Rat
Regulatory Status:	RUO
Clonality:	monoclonal
Emission Maximum:	518 nm
Excitation Maximum:	490 to 495 nm
Isotype:	IgG2a
Order number:	BY978670

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration Unit mg/mL Concentration 0.5 Quantity 0.1 mg Volume 0.2... more

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CyFlow™ CD45R FITC

Concentration Unit	mg/mL
Concentration	0.5
Quantity	0.1 mg
Volume	0.2
Immunogen	Abelson murine leukemia virus-induced pre-B tumor cells
Background Information	CD45R is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
Usage	The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
Storage	Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability	Do not use after expiration date stamped on vial label.

Specific References

| Watanabe Y, Akaike T: Activation signal induces the expression of B cell‑specific CD45R epitope (6B2) on murine T cells. Scand·J·Immunol. 1994·May; 39(5):419‑25. <·PMID:·7514808·> | Rada C, Ehrenstein MR, Neuberger MS, Milstein C: Hot spot focusing of somatic hypermutation in MSH2‑deficient mice suggests two stages of mutational targeting. Immunity. 1998·Jul; 9(1):135‑41. <·PMID:·9697843·> | Tsurui H, Nishimura H, Hattori S, Hirose S, Okumura K, Shirai T: Seven‑color fluorescence imaging of tissue samples based on Fourier spectroscopy and singular value decomposition. J·Histochem·Cytochem. 2000·May; 48(5):653‑62. <·PMID:·10769049·> | Cappione AJ, Pugh-Bernard AE, Anolik JH, Sanz I: Lupus IgG VH4.34 antibodies bind to a 220‑kDa glycoform of CD45/B220 on the surface of human B lymphocytes. J·Immunol. 2004·Apr·1; 172(7):4298‑307. <·PMID:·15034044·> | Montecino-Rodriguez E, Leathers H, Dorshkind K: Identification of a B‑1 B cell‑specified progenitor. Nat·Immunol. 2006·Mar; 7(3):293‑301. <·PMID:·16429139·> | Rothaeusler K, Baumgarth N: Evaluation of intranuclear BrdU detection procedures for use in multicolor flow cytometry. Cytometry·A. 2006·Apr; 69(4):249‑59. <·PMID:·16538653·> | Lochhead RB, Sonderegger FL, Ma Y, Brewster JE, Cornwall D, Maylor-Hagen H, Miller JC, Zachary JF, Weis JH, Weis JJ: Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi‑infected joint tissue. J·Immunol. 2012·Sep·1; 189(5):2488‑501. <·PMID:·22851707·>

Welcome toSysmex Flow Cytometry Other European Country!

Welcome to
Sysmex Flow Cytometry Other European Country!