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CyFlow™ CD63 PE-Cy5
| Application: | Flow cytometry |
| Isotype: | IgG1 |
| Clone: | MEM-259 |
| Alternative Name: | LAMP-3, LIMP, MLA1 |
| Antigen: | CD63 |
| Emission Maximum: | 670 nm |
| Format/Fluorochrome: | PE-Cy5 |
| Excitation Maximum: | 496 nm, 565 nm |
| Clonality: | monoclonal |
| Laser: | Blue, Green, Yellow |
| Field of Interest: | Endocytosis, Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Target Species: | Human |
| Order number: | AS197582 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 0.4 mL Immunogen Human Acute Lymphocytic Leukemia (ALL) T... more
Product information "CyFlow™ CD63 PE-Cy5"
| Quantity | 100 tests |
| Volume | 0.4 mL |
| Immunogen | Human Acute Lymphocytic Leukemia (ALL) T cells |
| Background Information | CD63 (LAMP-3; lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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