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CyFlow™ CD64 PE-Cy5
| Application: | Flow cytometry |
| Excitation Maximum: | 496 nm, 565 nm |
| Alternative Name: | FcγRI |
| Antigen: | CD64 |
| Emission Maximum: | 670 nm |
| Format/Fluorochrome: | PE-Cy5 |
| Target Species: | Human, Non-Human Primates |
| Isotype: | IgG1 |
| Laser: | Blue, Green, Yellow |
| Clonality: | monoclonal |
| Field of Interest: | Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Clone: | 10.1 |
| Order number: | CM807316 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA III—WS Code M-250 Quantity 100 tests Volume 0.4 mL Immunogen... more
Product information "CyFlow™ CD64 PE-Cy5"
| HLDA Workshop | HLDA III—WS Code M-250 |
| Quantity | 100 tests |
| Volume | 0.4 mL |
| Immunogen | Rheumatoid synovial fluid cells and fibronectin purified human monocytes |
| Background Information | CD64 (FcγRI) is a cell surface receptor for Fc region of IgG. It is composed of specific ligand binding α subunit and promiscuous γ subunit, which is indispensable for tyrosine-based signaling. However, even the α subunit can transduce signals leading to cellular effector functions. The isoform FcγRIa1 binds human IgG with high affinity, has limited myeloid cell distribution, and a relatively large intracellular domain. Products of related genes include FcγRIb and FcγRIc isoforms, but these specify low affinity IgG receptors if functionally expressed at all. Besides a role in antigen clearance, FcgammaRI (a1) can potently enhance MHC class I and II antigen presentation in vitro and in vivo. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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