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CyFlow™ CD68 Purified
Application: | Flow cytometry, Immunohistochemistry (frozen sections) |
Clonality: | monoclonal |
Target Species: | Human |
Regulatory Status: | RUO |
Isotype: | IgG2b |
Source Species: | Mouse |
Field of Interest: | Immunophenotyping |
Format/Fluorochrome: | Purified |
Antigen: | CD68 |
Alternative Name: | gp110, Macrosialin |
Clone: | Y1/82A |
Order number: | CY184980 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD68 Purified"
Concentration Unit | mg/mL |
Concentration | 1 |
Quantity | 0.1 mg |
Volume | 0.1 mL |
Immunogen | Lysosomal contents of lung macrophages |
Background Information | CD68 (LAMP4, SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms). |
Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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