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CyFlow™ CD68 Purified

CyFlow™ CD68 Purified
Application: Flow cytometry, Immunohistochemistry (frozen sections)
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Isotype: IgG2b
Source Species: Mouse
Field of Interest: Immunophenotyping
Format/Fluorochrome: Purified
Antigen: CD68
Alternative Name: gp110, Macrosialin
Clone: Y1/82A
Order number: CY184980
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD68 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenLysosomal contents of lung macrophages
Background InformationCD68 (LAMP4, SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms).
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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