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CyFlow™ CD117 Purified

Application:	Flow cytometry, Immunocytochemistry, Immunohistochemistry (frozen sections), Immunoprecipitation
Alternative Name:	c-kit, SCFR
Antigen:	CD117
Field of Interest:	Immunophenotyping, Phosphorylation
Target Species:	Cow, Human, Non-Human Primates
Clonality:	monoclonal
Isotype:	IgG1
Format/Fluorochrome:	Purified
Source Species:	Mouse
Regulatory Status:	RUO
Clone:	104D2
Order number:	AH410546

HLDA Workshop HLDA VI—WS Code C-30 Concentration Unit mg/mL Concentration 1... more

Product information "CyFlow™ CD117 Purified"

HLDA Workshop	HLDA VI—WS Code C-30
Concentration Unit	mg/mL
Concentration	1
Quantity	0.1 mg
Volume	0.1 mL
Immunogen	MOLM-1 megakaryocytic cells
Background Information	CD117 (c-Kit) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 can lead to growth and progression of tumors. After binding of its ligand, SCF (stem cell factor), CD117 is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
Storage	Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability	Do not use after expiration date stamped on vial label.

Safety Data Sheet

Technical Data Sheet

CyFlow CD117 Purified (104D2) AH410546 TDS RUO.pdf

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