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CyFlow™ CD23 PE-Cy7

CyFlow™ CD23 PE-Cy7
Application: Flow cytometry
Excitation Maximum: 496 nm, 565 nm
Alternative Name: BLAST-2, FcɛRII
Antigen: CD23
Emission Maximum: 785 nm
Format/Fluorochrome: PE-Cy7
Isotype: IgG1
Laser: Blue, Green, Yellow
Clonality: monoclonal
Field of Interest: Immunophenotyping
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clone: EBVCS-5
Order number: CH091551
Quantity 100 tests Volume 0.4 mL Immunogen EBV-transformed human cells Background... more
Product information "CyFlow™ CD23 PE-Cy7"
Quantity100 tests
Volume0.4 mL
ImmunogenEBV-transformed human cells
Background InformationCD23 (FcεRII, BLAST-2), the low affinity IgE receptor, is a 45 kDa type II membrane glycoprotein expressed on eosinophils, follicular dendritic cells, Langerhans cells, mature B cells (mainly upon activation), EBV-transformed lymphoblasts, monocytes, and subpopulation of platelets. CD23 mediates IgE-dependent cytotoxicity by eosinophils and macrophages, and downregulates IgE secretion in response to high levels of IgE, involving release of pro-inflammatory cytokines.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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