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CyFlow™ CD25 FITC
Application: | Flow cytometry |
Target Species: | Mouse |
Alternative Name: | IL2Rα, p55, TAC |
Antigen: | CD25 |
Source Species: | Rat |
Field of Interest: | Immunophenotyping, MHC |
Isotype: | IgG1 |
Clonality: | monoclonal |
Emission Maximum: | 518 nm |
Excitation Maximum: | 490 to 495 nm |
Laser: | Blue |
Regulatory Status: | RUO |
Format/Fluorochrome: | FITC |
Clone: | PC61.5 |
Order number: | BG913987 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 0,5 Quantity 0.1 mg Volume 0.2 mL... more
Product information "CyFlow™ CD25 FITC"
Concentration Unit | mg/mL |
Concentration | 0,5 |
Quantity | 0.1 mg |
Volume | 0.2 mL |
Immunogen | B6.1 CTL cell line |
Background Information | CD25 (IL2Rα, Tac) is a ligand-binding α subunit of interleukin 2 receptor (IL2R). Together with β and γ subunit CD25 constitues the high affinity IL2R, whereas CD25 alone serves as the low affinity IL2R. CD25 expression rapidly increases upon T cell activation. The 55 kDa CD25 molecule is enzymatically cleaved and shed from the cell surface as a soluble 45 kDa s-Tac, whose concentration in serum can be used as a marker of T cell activation. Expression of CD25 indicates the neoplastic phenotype of mast cells. CD25+ CD4+ FoxP3+ regulatory cells (Treg cells) play a crucial role in the control of organ-specific autoimmune diseases. |
Usage | The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator. |
Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow™ CD25 FITC (MEM-181) BZ784311 TDS US,CA EN.pdf
- CyFlow CD25 FITC (MEM-181) AH959493 TDS RUO.pdf
- CyFlow CD25 FITC (PC61.5) BG913987 TDS RUO.pdf
- CyFlow CD25 FITC (MEM-181) BZ784311 TDS ASR EN.pdf
Certificate Of Analysis
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