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CyFlow™ CD33 PE-Cy5
| Application: | Flow cytometry |
| Isotype: | IgG1 |
| Alternative Name: | p67, SIGLECT-3 |
| Antigen: | CD33 |
| Emission Maximum: | 670 nm |
| Format/Fluorochrome: | PE-Cy5 |
| Target Species: | Human, Non-Human Primates |
| Excitation Maximum: | 496 nm, 565 nm |
| Clonality: | monoclonal |
| Laser: | Blue, Green, Yellow |
| Field of Interest: | Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Clone: | WM53 |
| Order number: | AR844757 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA IV—WS Code M-505 Quantity 100 tests Volume 0.4 mL Immunogen... more
Product information "CyFlow™ CD33 PE-Cy5"
| HLDA Workshop | HLDA IV—WS Code M-505 |
| Quantity | 100 tests |
| Volume | 0.4 mL |
| Immunogen | Human Acute Myelogenous Leukemia (AML) cells |
| Background Information | CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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