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CyFlow™ CD2 Low Endotoxin
| Application: | Flow cytometry, Functional assays |
| Clonality: | monoclonal |
| Target Species: | Human |
| Regulatory Status: | RUO |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping |
| Isotype: | IgG1 |
| Antigen: | CD2 |
| Alternative Name: | LFA-2 |
| Clone: | TS1/8 |
| Format/Fluorochrome: | Low Endotoxin |
| Order number: | CK864668 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA V—WS Code S025 Concentration Unit mg/mL Concentration 1... more
Product information "CyFlow™ CD2 Low Endotoxin"
| HLDA Workshop | HLDA V—WS Code S025 |
| Concentration Unit | mg/mL |
| Concentration | 1 |
| Quantity | 0.1 mg |
| Volume | 0.1 mL |
| Immunogen | Cytotoxic T lymphocytes |
| Background Information | CD2 (LFA-2) belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection. |
| Storage Buffer | The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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