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CyFlow™ CD3 PE-Cy7
Application: | Flow cytometry |
Isotype: | IgG1 |
Target Species: | Human, Non-Human Primates |
Alternative Name: | Leu4, T3 |
Antigen: | CD3 |
Emission Maximum: | 785 nm |
Format/Fluorochrome: | PE-Cy7 |
Excitation Maximum: | 496 nm, 565 nm |
Clonality: | monoclonal |
Laser: | Blue, Green, Yellow |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Clone: | SK7 |
Order number: | BQ006366 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA II—WS Code T118 HLDA III—WS Code T492 Quantity 100 tests Volume... more
Product information "CyFlow™ CD3 PE-Cy7"
HLDA Workshop | HLDA II—WS Code T118 HLDA III—WS Code T492 |
Quantity | 100 tests |
Volume | 0.4 mL |
Immunogen | Human thymocytes |
Background Information | CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3γ, CD3 δ, CD3ε and CD3ζ. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow™ CD3 PE-Cy7 (SK7) BX271984 TDS US,CA EN.pdf
- CyFlow CD3 PE-Cy7 (145-2C11) CT140267 TDS RUO.pdf
- CyFlow CD3 PE-Cy7 (SK7) BQ006366 TDS RUO.pdf
- CyFlow CD3 PE-Cy7 (UCHT1) AZ391761 TDS RUO.pdf
- CyFlow CD3 PE-Cy7 (SK7) BX271984 TDS ASR EN.pdf
Instruction for Use
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU DE DE.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU CZ CZ.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU CZ CZ.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU DE DE.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU DK DK.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU ES ES.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU FR FR.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU GB EN.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU GR EL.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU IT IT.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU NL NL.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU NO NO.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU PL PL.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU PT PT.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU RU RU.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU SE SV.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU SK SK.pdf
- CyFlow CD3 PE-Cy7 (SK7) BL640854 IFU TR TR.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU DE DE.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU DK DK.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU ES ES.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU FR FR.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU GB EN.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU GR EL.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU IT IT.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU NL NL.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU NO NO.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU PL PL.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU PT PT.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU RU RU.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU SE SV.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU SK SK.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU TR TR.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU BG BG.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU HR HR.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU RO RO.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU SI SL.pdf
- CyFlow CD3 PE-Cy7 (SK7) BC891444 IFU RS SR.pdf
ECDoC
Certificate Of Analysis
- CyFlow CD3 PE-Cy7 BL640854 COA 901851.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 901913.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 902908.pdf
- CyFlow CD3 PE-Cy7 BL640854 COA 902908.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 904371.pdf
- CyFlow CD3 PE-Cy7 BL640854 COA 904482.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 904482.pdf
- CyFlow CD3 PE-Cy7 BC891444 COA 905301.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 905301.pdf
- CyFlow CD3 PE-Cy7 BC891444 COA 905909.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 905909.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 907424.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 907708.pdf
- CyFlow CD3 PE-Cy7 BC891444 COA 907863.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 907863.pdf
- CyFlow CD3 PE-Cy7 BX271984 COA 908842.pdf
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