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CyFlow™ CD3 FITC
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Format/Fluorochrome: | FITC |
| Target Species: | Human, Non-Human Primates |
| Regulatory Status: | RUO |
| Laser: | Blue |
| Excitation Maximum: | 490 to 495 nm |
| Emission Maximum: | 518 nm |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping |
| Isotype: | IgG1 |
| Antigen: | CD3 |
| Alternative Name: | Leu4, T3 |
| Clone: | UCHT1 |
| Order number: | AB614014 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA I—WS Code T 3 HLDA III—WS Code T 126 HLDA III—WS Code T 471 HLDA VI—WS... more
Product information "CyFlow™ CD3 FITC"
| HLDA Workshop | HLDA I—WS Code T 3 HLDA III—WS Code T 126 HLDA III—WS Code T 471 HLDA VI—WS Code T 6T-CD3.1 |
| Quantity | 100 tests |
| Volume | 2.0 mL |
| Immunogen | Human thymocytes followed by Sezary T cells |
| Background Information | CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3γ, CD3 δ, CD3ε and CD3ζ. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow™ CD3 FITC (UCHT1) CF225414 TDS US,CA EN.pdf
- CyFlow CD3 FITC (145-2C11) AJ219456 TDS RUO.pdf
- CyFlow CD3 FITC (MEM-57) BA030994 TDS RUO.pdf
- CyFlow CD3 FITC (UCHT1) AB614014 TDS RUO.pdf
- CyFlow CD3 FITC (UCHT1) CF225414 TDS ASR EN.pdf
Instruction for Use
- CyFlow CD3 FITC (UCHT1) AV797318 IFU DE DE.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU CZ CZ.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU DK DK.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU GR EL.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU IT IT.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU NL NL.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU NO NO.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU PL PL.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU RU RU.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU SE SV.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU SK SK.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU TR TR.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU CZ CZ.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU GB EN.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU ES ES.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU FR FR.pdf
- CyFlow CD3 FITC (UCHT1) AV797318 IFU PT PT.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU DE DE.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU DK DK.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU ES ES.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU FR FR.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU GB EN.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU GR EL.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU IT IT.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU NL NL.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU NO NO.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU PL PL.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU PT PT.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU RU RU.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU SE SV.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU SK SK.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU TR TR.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU BG BG.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU HR HR.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU RO RO.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU SI SL.pdf
- CyFlow CD3 FITC (UCHT1) CK579259 IFU RS SR.pdf
ECDoC
Certificate Of Analysis
- CyFlow CD3 FITC AV797318 COA 901793.pdf
- CyFlow CD3 FITC_CF225414_COA_901793.pdf
- CyFlow CD3 FITC AV97318 COA 903481.pdf
- CyFlow CD3 FITC CF225414 COA 903481.pdf
- CyFlow CD3 FITC CK579259 COA 903481.pdf
- CyFlow CD3 FITC CK579259 COA 905135.pdf
- CyFlow CD3 FITC CF225414 COA 905135.pdf
- CyFlow CD3 FITC CK579259 COA 906228.pdf
- CyFlow CD3 FITC CF225414 COA 906228.pdf
- CyFlow CD3 FITC CF225414 COA 907986.pdf
- CyFlow CD3 FITC CK579259 COA 907986.pdf
- CyFlow CD3 FITC CK579259 COA 908949.pdf
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