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CyFlow™ CD11b Alexa Fluor™ 488
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Target Species: | Human, Non-Human Primates |
| Regulatory Status: | RUO |
| Laser: | Blue |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping |
| Isotype: | IgG1 |
| Format/Fluorochrome: | Alexa Fluor™ 488 |
| Excitation Maximum: | 495 nm |
| Emission Maximum: | 519 nm |
| Antigen: | CD11b |
| Alternative Name: | Mac-1 |
| Clone: | ICRF44 |
| Order number: | CW580162 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA IV—WS Code M047 Quantity 100 tests Volume 0.4 mL Immunogen... more
Product information "CyFlow™ CD11b Alexa Fluor™ 488"
| HLDA Workshop | HLDA IV—WS Code M047 |
| Quantity | 100 tests |
| Volume | 0.4 mL |
| Immunogen | Rheumatoid synovial cells and human monocytes |
| Background Information | CD11b (integrin αM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with CD18 (integrin β2 subunit); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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