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CyFlow™ CD11c FITC
Application: | Flow cytometry |
Clonality: | monoclonal |
Format/Fluorochrome: | FITC |
Target Species: | Human, Non-Human Primates |
Regulatory Status: | RUO |
Laser: | Blue |
Excitation Maximum: | 490 to 495 nm |
Emission Maximum: | 518 nm |
Source Species: | Mouse |
Field of Interest: | Immunophenotyping |
Isotype: | IgG1 |
Antigen: | CD11c |
Alternative Name: | p150 |
Clone: | BU15 |
Order number: | BE721788 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA III—WS Code M 256 HLDA V—WS Code AS S143 HLDA VI—WS Code AS Ref.6... more
Product information "CyFlow™ CD11c FITC"
HLDA Workshop | HLDA III—WS Code M 256 HLDA V—WS Code AS S143 HLDA VI—WS Code AS Ref.6 |
Quantity | 100 tests |
Volume | 2.0 mL |
Immunogen | Dendritic cells of synovial fluid |
Background Information | CD11c (αX integrin subunit) forms complex with CD18 (β2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other β2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
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