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CyFlow™ CD11c Purified

CyFlow™ CD11c Purified
Antigen: CD11c
Alternative Name: p150
Clone: BU15
Application: Flow cytometry, Immunohistochemistry (frozen sections), Immunoprecipitation
Format/Fluorochrome: Purified
Target Species: Human, Non-Human Primates
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Isotype: IgG1
Order number: CF757356

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration 1 mg/ml Quantity 0.1 mg Volume 0.1 ml Immunogen Dendritic cells of... more
CyFlow™ CD11c Purified
Concentration1 mg/ml
Quantity0.1 mg
Volume0.1 ml
ImmunogenDendritic cells of synovial fluid
SpecifityThe mouse monoclonal antibody BU15 reacts with CD11c antigen, a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
Background InformationCD11c (αX integrin subunit) forms complex with CD18 (β2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other β2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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