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CyFlow™ CD21 PE

CyFlow™ CD21 PE
Application: Flow cytometry
Emission Maximum: 576 nm
Clone: LT21
Alternative Name: C3dR, CR2, EBV-R
Antigen: CD21
Target Species: Cow, Dog, Human, Pig
Isotype: IgG1
Excitation Maximum: 496 nm, 565 nm
Clonality: monoclonal
Laser: Blue, Green, Yellow
Format/Fluorochrome: PE
Field of Interest: Immunophenotyping
Source Species: Mouse
Regulatory Status: RUO
Order number: AC533349
HLDA Workshop HLDA VI—WS Code B CD21.1 Quantity 100 tests Volume 2.0 mL Immunogen... more
Product information "CyFlow™ CD21 PE"
HLDA WorkshopHLDA VI—WS Code B CD21.1
Quantity100 tests
Volume2.0 mL
ImmunogenIM9 human B-lymphoblastoid cell line
Background InformationCD21 (CR2; complement receptor 2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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