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CyFlow™ CD24 Pacific Blue™

CyFlow™ CD24 Pacific Blue™
Application: Flow cytometry
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping
Isotype: IgG1
Format/Fluorochrome: Pacific Blue™
Laser: Violet
Excitation Maximum: 400 to 410 nm
Emission Maximum: 455 nm
Antigen: CD24
Alternative Name: BA 1, HAS
Clone: SN3
Order number: CK623341
HLDA Workshop HLDA IV—WS Code B 136 HLDA V—WS Code B CD24.7 Quantity 100 tests Volume... more
Product information "CyFlow™ CD24 Pacific Blue™"
HLDA WorkshopHLDA IV—WS Code B 136 HLDA V—WS Code B CD24.7
Quantity100 tests
Volume0.4 mL
ImmunogenGlycoproteins purified from human NALM-1 cell line
Background InformationCD24 (BA 1, HSA) is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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