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CyFlow™ CD42b PE

CyFlow™ CD42b PE
Application: Flow cytometry
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Laser: Blue, Green, Yellow
Source Species: Mouse
Field of Interest: Immunophenotyping
Format/Fluorochrome: PE
Excitation Maximum: 496 nm, 565 nm
Emission Maximum: 576 nm
Isotype: IgG1
Antigen: CD42b
Alternative Name: GPIba
Clone: AK2
Order number: AE407501
HLDA Workshop HLDA V—WS Code P024 Quantity 100 tests Volume 1.0 mL Immunogen... more
Product information "CyFlow™ CD42b PE"
HLDA WorkshopHLDA V—WS Code P024
Quantity100 tests
Volume1.0 mL
ImmunogenHuman platelets
Background InformationCD42b (GPIb α) composes together with GPIb β, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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