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CyFlow™ CD44 APC

CyFlow™ CD44 APC
Application: Flow cytometry
Target Species: Cat, Dog, Horse, Human, Mouse
Clone: IM7
Alternative Name: H-CAM, Pgp-1
Antigen: CD44
Source Species: Rat
Emission Maximum: 660 nm
Clonality: monoclonal
Excitation Maximum: 650 nm
Laser: Red
Format/Fluorochrome: APC
Field of Interest: Immunophenotyping
Isotype: IgG2b
Regulatory Status: RUO
Order number: CX908120
Concentration Unit mg/mL Concentration 0,5 Quantity 0.1 mg Volume 0.2 mL... more
Product information "CyFlow™ CD44 APC"
Concentration Unitmg/mL
Concentration0,5
Quantity0.1 mg
Volume0.2 mL
ImmunogenDexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1
Background InformationCD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumor growth and metastasis, antiapoptosis and directional motility of cancer cells.
UsageThe reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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