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CyFlow™ CD44 APC
| Application: | Flow cytometry |
| Target Species: | Cat, Dog, Horse, Human, Mouse |
| Clone: | IM7 |
| Alternative Name: | H-CAM, Pgp-1 |
| Antigen: | CD44 |
| Source Species: | Rat |
| Emission Maximum: | 660 nm |
| Clonality: | monoclonal |
| Excitation Maximum: | 650 nm |
| Laser: | Red |
| Format/Fluorochrome: | APC |
| Field of Interest: | Immunophenotyping |
| Isotype: | IgG2b |
| Regulatory Status: | RUO |
| Order number: | CX908120 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 0,5 Quantity 0.1 mg Volume 0.2 mL... more
Product information "CyFlow™ CD44 APC"
| Concentration Unit | mg/mL |
| Concentration | 0,5 |
| Quantity | 0.1 mg |
| Volume | 0.2 mL |
| Immunogen | Dexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1 |
| Background Information | CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumor growth and metastasis, antiapoptosis and directional motility of cancer cells. |
| Usage | The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator. |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
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