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CyFlow™ CD44 FITC
| Application: | Flow cytometry |
| Field of Interest: | Immunophenotyping |
| Alternative Name: | H-CAM, Pgp-1 |
| Antigen: | CD44 |
| Target Species: | Dog, Human, Pig |
| Isotype: | IgG1 |
| Source Species: | Mouse |
| Clonality: | monoclonal |
| Emission Maximum: | 518 nm |
| Excitation Maximum: | 490 to 495 nm |
| Laser: | Blue |
| Regulatory Status: | RUO |
| Format/Fluorochrome: | FITC |
| Clone: | MEM-263 |
| Order number: | CQ863904 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 2.0 mL Immunogen COS-7 African green monkey kidney cells... more
Product information "CyFlow™ CD44 FITC"
| Quantity | 100 tests |
| Volume | 2.0 mL |
| Immunogen | COS-7 African green monkey kidney cells |
| Background Information | CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumor growth and metastasis, antiapoptosis and directional motility of cancer cells. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
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