Welcome to
Sysmex Flow Cytometry Other European Country!

For ordering please make sure you are in your local shop.
If you are from Other European Country then please continue.
Otherwise please go to your country.

Go to my country Continue

Article successfully added.

CyFlow™ CD47 Purified

CyFlow™ CD47 Purified
Application: Flow cytometry, Immunohistochemistry (frozen sections), Western blot
Clonality: monoclonal
Target Species: Human, Non-Human Primates, Pig
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping
Format/Fluorochrome: Purified
Isotype: IgM
Antigen: CD47
Alternative Name: IAP
Clone: MEM-122
Order number: AV372758
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD47 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenCOS-7 African green monkey kidney cells
Background InformationCD47 (IAP; integrin-associated protein) is an ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions. Engagement of CD47 by soluble ligands or counter receptors modulates various signaling pathways, such as activation of heterotrimeric G proteins. Binding secreted thrombospondin-1, CD47 counteracts graft vascularization. CD47 acts also as a ligand for CD172a (SIRP α; signal regulatory protein α), an immune inhibitory receptor on macrophages; this interaction prevents phagocytosis of CD47-positive cells. Moreover, CD47-CD172a system affects cell migration, B cell adhesion and T cell activation. CD47 is also involved in modulation of chondrocyte responses to mechanical signals, and promotes neuronal development, being especially abundant in synapse-rich regions of brain and retina.
Storage BufferThe reagent is provided in Tris buffered saline (TBS) solution, pH ≈8.0, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Similar products
FITC
CyFlow™ CD1a FITC
Antigen: CD1a
Clone: SK9
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
PE
CyFlow™ CD1a PE
Antigen: CD1a
Clone: SK9
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
APC
CyFlow™ CD1a APC
Antigen: CD1a
Clone: SK9
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
Purified
CyFlow™ CD1a Purified
Antigen: CD1a
Clone: SK9
Application: Flow cytometry, Immunoprecipitation
Regulatory Status: RUO
Target Species: Human
Quantity: 0.1 mg
FITC
CyFlow™ CD1b FITC
Antigen: CD1b
Clone: SN13
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
Purified
CyFlow™ CD1b Purified
Antigen: CD1b
Clone: SN13
Application: Flow cytometry, Immunohistochemistry, Immunoprecipitation
Regulatory Status: RUO
Target Species: Human
Quantity: 0.1 mg
PE
CyFlow™ CD1c PE
Antigen: CD1c
Clone: L161
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
Purified
CyFlow™ CD1c Purified
Antigen: CD1c
Clone: L161
Application: Flow cytometry, Immunohistochemistry, Immunoprecipitation
Regulatory Status: RUO
Target Species: Human
Quantity: 0.1 mg

 

Need more information?
Need more information?
Service Hotline | Contact | Benefits
Service hotline
tel: +49 (40) 527 26 0 Mon-Fri, 9 am - 5 pm

Contact
Use our contact form