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CyFlow™ CD59 Azide Free

CyFlow™ CD59 Azide Free
Application: Flow cytometry, Functional assays
Clonality: monoclonal
Target Species: Human, Pig
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping
Isotype: IgM
Format/Fluorochrome: Azide Free
Antigen: CD59
Alternative Name: Protectin H19
Clone: MEM-129
Order number: BR267721
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD59 Azide Free"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman peripheral blood lymphocytes
Background InformationCD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.
Storage BufferThe reagent is provided in azide-free HEPES buffered saline (HBS) solution, pH ≈7.0; 0.2 µm filter sterilized.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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