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CyFlow™ CD62L Purified

CyFlow™ CD62L Purified
Antigen: CD62L
Alternative Name: L-Selectin
Clone: MEL-14
Application: Flow cytometry, Functional assays, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation
Format/Fluorochrome: Purified
Target Species: Mouse
Field of Interest: Immunophenotyping, MHC
Species of Origin: Rat
Regulatory Status: RUO
Clonality: monoclonal
Isotype: IgG2a
Order number: CX209714

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration 1 mg/ml Quantity 0.1 mg Volume 0.1 ml Immunogen C3H/eb mouse B cell... more
CyFlow™ CD62L Purified
Concentration1 mg/ml
Quantity0.1 mg
Volume0.1 ml
ImmunogenC3H/eb mouse B cell lymphoma 38C-13
SpecifityThe rat monoclonal antibody MEL-14 recognizes mouse CD62L, a 75 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
Background InformationCD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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