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CyFlow™ CD62P Biotin
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Target Species: | Human, Non-Human Primates |
| Regulatory Status: | RUO |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping |
| Isotype: | IgG1 |
| Format/Fluorochrome: | Biotin |
| Antigen: | CD62P |
| Alternative Name: | P-selectin |
| Clone: | AK4 |
| Order number: | CU508361 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA VI—WS Code P-44 Concentration Unit mg/mL Concentration 1... more
Product information "CyFlow™ CD62P Biotin"
| HLDA Workshop | HLDA VI—WS Code P-44 |
| Concentration Unit | mg/mL |
| Concentration | 1 |
| Quantity | 0.1 mg |
| Volume | 0.1 mL |
| Immunogen | Human platelets |
| Background Information | CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster. |
| Usage | The reagent is designed for indirect immunofluorescence analysis by Flow Cytometry. Working concentrations should be determined by the investigator. |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
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