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CyFlow™ CD68 PE

CyFlow™ CD68 PE
Application: Flow cytometry
Laser: Blue, Green, Yellow
Alternative Name: gp110, Macrosialin
Antigen: CD68
Emission Maximum: 576 nm
Excitation Maximum: 496 nm, 565 nm
Format/Fluorochrome: PE
Clonality: monoclonal
Field of Interest: Immunophenotyping
Source Species: Mouse
Isotype: IgG2b
Regulatory Status: RUO
Target Species: Human
Clone: Y1/82A
Order number: BL731690
Quantity 100 tests Volume 1.0 mL Immunogen Lysosomal contents of lung macrophages... more
Product information "CyFlow™ CD68 PE"
Quantity100 tests
Volume1.0 mL
ImmunogenLysosomal contents of lung macrophages
Background InformationCD68 (LAMP4, SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms).
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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