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CyFlow™ CD79a APC
Application: | Flow cytometry |
Target Species: | Chicken, Cow, Guinea pig, Horse, Human, Mouse, Opossum, Pig, Rabbit, Rat |
Clone: | HM57 |
Alternative Name: | IgA, MB-1, MB1 |
Antigen: | CD79a |
Clonality: | monoclonal |
Isotype: | IgG1 |
Emission Maximum: | 660 nm |
Excitation Maximum: | 650 nm |
Laser: | Red |
Format/Fluorochrome: | APC |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Order number: | AJ298129 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA V—WS Code BC cB018 HLDA VI—WS Code BP 193 HLDA VI—WS Code BP 89 HLDA VI—WS... more
Product information "CyFlow™ CD79a APC"
HLDA Workshop | HLDA V—WS Code BC cB018 HLDA VI—WS Code BP 193 HLDA VI—WS Code BP 89 HLDA VI—WS Code B B103 HLDA VI—WS Code B CD79.4 |
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Synthetic peptide corresponding to amino acids 202-216 of human CD79a |
Background Information | CD79a (Ig α, MB1) forms disulfide-linked heterodimer with CD79b (Ig β, B29). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with λ5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow™ CD79a APC (HM57) BL177563 TDS US,CA EN.pdf
- CyFlow CD79a APC (HM47) AQ406223 TDS RUO.pdf
- CyFlow CD79a APC (HM57) AJ298129 TDS RUO.pdf
- CyFlow CD79a APC (HM57) BL177563 TDS ASR EN.pdf
Instruction for Use
- CyFlow CD79a APC (HM57) BK592023 IFU CZ CZ.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU CZ CZ.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU DE DE.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU DK DK.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU ES ES.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU FR FR.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU GB EN.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU GR EL.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU IT IT.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU NL NL.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU NO NO.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU PL PL.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU PT PT.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU RU RU.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU SE SV.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU SK SK.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU TR TR.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU DE DE.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU DK DK.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU ES ES.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU FR FR.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU GB EN.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU GR EL.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU IT IT.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU NL NL.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU NO NO.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU PL PL.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU PT PT.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU RU RU.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU SE SV.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU SK SK.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU TR TR.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU BG BG.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU HR HR.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU RO RO.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU SI SL.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU RS SR.pdf
ECDoC
Certificate Of Analysis
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