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CyFlow™ CD79b Purified

CyFlow™ CD79b Purified
Application: Flow cytometry, Immunoprecipitation, Western blot
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping
Format/Fluorochrome: Purified
Isotype: IgG1
Antigen: CD79b
Alternative Name: B29, IgB
Clone: CB3-1
Order number: AC144778
HLDA Workshop HLDA VI—WS Code CD79.1 Concentration Unit mg/mL Concentration 1... more
Product information "CyFlow™ CD79b Purified"
HLDA WorkshopHLDA VI—WS Code CD79.1
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenFraction of Ig-associated molecules isolated from Ramos B cells
Background InformationCD79b (IgB, B29) forms disulfide-linked heterodimer with CD79a (IgA, MB-1, MB1). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with λ5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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