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CyFlow™ CD79b Purified
Application: | Flow cytometry, Immunoprecipitation, Western blot |
Clonality: | monoclonal |
Target Species: | Human |
Regulatory Status: | RUO |
Source Species: | Mouse |
Field of Interest: | Immunophenotyping |
Format/Fluorochrome: | Purified |
Isotype: | IgG1 |
Antigen: | CD79b |
Alternative Name: | B29, IgB |
Clone: | CB3-1 |
Order number: | AC144778 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA VI—WS Code CD79.1 Concentration Unit mg/mL Concentration 1... more
Product information "CyFlow™ CD79b Purified"
HLDA Workshop | HLDA VI—WS Code CD79.1 |
Concentration Unit | mg/mL |
Concentration | 1 |
Quantity | 0.1 mg |
Volume | 0.1 mL |
Immunogen | Fraction of Ig-associated molecules isolated from Ramos B cells |
Background Information | CD79b (IgB, B29) forms disulfide-linked heterodimer with CD79a (IgA, MB-1, MB1). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with λ5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. |
Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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