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CyFlow™ CD105 APC
Application: | Flow cytometry |
Clonality: | monoclonal |
Target Species: | Human, Rat |
Regulatory Status: | RUO |
Source Species: | Mouse |
Field of Interest: | Immunophenotyping |
Format/Fluorochrome: | APC |
Laser: | Red |
Excitation Maximum: | 650 nm |
Emission Maximum: | 660 nm |
Isotype: | IgG2a |
Antigen: | CD105 |
Alternative Name: | Endoglin |
Clone: | MEM-226 |
Order number: | BG489749 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Recombinant Vaccinia virus containing the... more
Product information "CyFlow™ CD105 APC"
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Recombinant Vaccinia virus containing the human CD105 cDNA |
Background Information | CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFβR-2 as a receptor for TGFβ-1 and TGFβ-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonizes the inhibitory effects of TGFβ-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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