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CyFlow™ CD120a Low Endotoxin

CyFlow™ CD120a Low Endotoxin
Application: Flow cytometry, Functional assays, Immunohistochemistry, Immunoprecipitation
Isotype: IgG2a
Alternative Name: p55, TNFR1, TNFRp55, TNFRSF1A
Antigen: CD120a
Field of Interest: Immunophenotyping, Signaling
Format/Fluorochrome: Low Endotoxin
Clonality: monoclonal
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clone: H398
Order number: CP892530
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD120a Low Endotoxin"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenRecombinant full length human CD120a
Background InformationCD120a (TNF R1,TNFR55 or TNFRSF1A) is a 55 kDa receptor for tumor necrosis factor α and it is expressed in most tissues. By binding its trimeric ligand the CD120a protein forms trimers and the conformation change leads to dissociation of the inhibitory factor SODD from its intracellular death domain and in formation of signaling platform. CD120a can mediate apoptosis, and function as a regulator of inflammation. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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