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CyFlow™ CD120a Low Endotoxin
| Application: | Flow cytometry, Functional assays, Immunohistochemistry, Immunoprecipitation |
| Isotype: | IgG2a |
| Alternative Name: | p55, TNFR1, TNFRp55, TNFRSF1A |
| Antigen: | CD120a |
| Field of Interest: | Immunophenotyping, Signaling |
| Format/Fluorochrome: | Low Endotoxin |
| Clonality: | monoclonal |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Target Species: | Human |
| Clone: | H398 |
| Order number: | CP892530 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD120a Low Endotoxin"
| Concentration Unit | mg/mL |
| Concentration | 1 |
| Quantity | 0.1 mg |
| Volume | 0.1 mL |
| Immunogen | Recombinant full length human CD120a |
| Background Information | CD120a (TNF R1,TNFR55 or TNFRSF1A) is a 55 kDa receptor for tumor necrosis factor α and it is expressed in most tissues. By binding its trimeric ligand the CD120a protein forms trimers and the conformation change leads to dissociation of the inhibitory factor SODD from its intracellular death domain and in formation of signaling platform. CD120a can mediate apoptosis, and function as a regulator of inflammation. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. |
| Storage Buffer | The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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