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CyFlow™ CD140b PE

CyFlow™ CD140b PE
Application: Flow cytometry
Excitation Maximum: 496 nm, 565 nm
Alternative Name: PDGFRB, PDGRF1
Antigen: CD140b
Field of Interest: Immunophenotyping, Signaling
Isotype: IgG1
Emission Maximum: 576 nm
Laser: Blue, Green, Yellow
Clonality: monoclonal
Format/Fluorochrome: PE
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clone: 18A2
Order number: CM847869
Quantity 100 tests Volume 2.0 mL Immunogen CD140b-transfected NIH 3T3 cells... more
Product information "CyFlow™ CD140b PE"
Quantity100 tests
Volume2.0 mL
ImmunogenCD140b-transfected NIH 3T3 cells
Background InformationCD140b (PDGF-RB; platelet-derived growth factor receptor β) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a (PDGF-RA). Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumors such as medulloblastoma.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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