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CyFlow™ CD146 PE
| Application: | Flow cytometry |
| Isotype: | IgG1 |
| Alternative Name: | MCAM, Mel-CAM, MUC18, s-endo |
| Antigen: | CD146 |
| Target Species: | Dog, Human, Mouse, Rabbit |
| Emission Maximum: | 576 nm |
| Clonality: | monoclonal |
| Excitation Maximum: | 496 nm, 565 nm |
| Laser: | Blue, Green, Yellow |
| Format/Fluorochrome: | PE |
| Field of Interest: | Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Clone: | P1H12 |
| Order number: | BG312271 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Cultured human umbilical cells... more
Product information "CyFlow™ CD146 PE"
| Quantity | 100 tests |
| Volume | 1.0 mL |
| Immunogen | Cultured human umbilical cells |
| Background Information | CD146 (MCAM; melanoma cell adhesion molecule or MUC18) is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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