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CyFlow™ CD146 Purified

Application:	Flow cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western blot
Alternative Name:	MCAM, Mel-CAM, MUC18, s-endo
Antigen:	CD146
Target Species:	Dog, Human, Mouse, Rabbit
Clonality:	monoclonal
Isotype:	IgG1
Format/Fluorochrome:	Purified
Field of Interest:	Immunophenotyping
Source Species:	Mouse
Regulatory Status:	RUO
Clone:	P1H12
Order number:	AV721526

Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more

Product information "CyFlow™ CD146 Purified"

Concentration Unit	mg/mL
Concentration	1
Quantity	0.1 mg
Volume	0.1 mL
Immunogen	Cultured human umbilical cells
Background Information	CD146 (MCAM; melanoma cell adhesion molecule or MUC18) is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
Storage	Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability	Do not use after expiration date stamped on vial label.

Safety Data Sheet

Technical Data Sheet

CyFlow CD146 Purified (P1H12) AV721526 TDS RUO.pdf

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