Article successfully added.
CyFlow™ CD148 Biotin
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Target Species: | Human |
| Regulatory Status: | RUO |
| Isotype: | IgG2b |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping, Phosphorylation |
| Format/Fluorochrome: | Biotin |
| Antigen: | CD148 |
| Alternative Name: | DEP-1, HPTP-a, SCC1 |
| Clone: | MEM-CD148/05 |
| Order number: | AE191755 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD148 Biotin"
| Concentration Unit | mg/mL |
| Concentration | 1 |
| Quantity | 0.1 mg |
| Volume | 0.1 mL |
| Immunogen | Human recombinant CD148 (amino acids 1-444) |
| Background Information | CD148 (HPTP-eta, DEP-1) is a transmembrane protein tyrosin phosphatase containing eight fibronectin type III extracellular domains. This protein is known to inhibit transduction of mitogenic signals in non-hematopoietic cells (fibroblasts, epithelial cells), and signal transduction downstream of T cell receptor, however, it also augments immunoreceptor signaling in B cells and macrophages via dephosphorylating C-terminal tyrosine of Src-family tyrosine kinases. CD148 expression increases after in vitro activation of peripheral blood leukocytes. It can be also used as marker of the most mature human thymocytes, and leukemic cells corresponding to this stadium of thymocyte differentiation. In contrast, in mice the CD148 expression sharply drops through the double positive stage to the single positive thymocytes. |
| Usage | The reagent is designed for indirect immunofluorescence analysis by Flow Cytometry. Working concentrations should be determined by the investigator. |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
Similar products
FITC
CyFlow™ CD1a FITC
| Antigen: | CD1a |
| Clone: | SK9 |
| Application: | Flow cytometry |
| Regulatory Status: | RUO |
| Target Species: | Human | Quantity: | 100 tests |
PE
CyFlow™ CD1a PE
| Antigen: | CD1a |
| Clone: | SK9 |
| Application: | Flow cytometry |
| Regulatory Status: | RUO |
| Target Species: | Human | Quantity: | 100 tests |
APC
CyFlow™ CD1a APC
| Antigen: | CD1a |
| Clone: | SK9 |
| Application: | Flow cytometry |
| Regulatory Status: | RUO |
| Target Species: | Human | Quantity: | 100 tests |
Purified
CyFlow™ CD1a Purified
| Antigen: | CD1a |
| Clone: | SK9 |
| Application: | Flow cytometry, Immunoprecipitation |
| Regulatory Status: | RUO |
| Target Species: | Human | Quantity: | 0.1 mg |
FITC
CyFlow™ CD1b FITC
| Antigen: | CD1b |
| Clone: | SN13 |
| Application: | Flow cytometry |
| Regulatory Status: | RUO |
| Target Species: | Human | Quantity: | 100 tests |
Purified
CyFlow™ CD1b Purified
| Antigen: | CD1b |
| Clone: | SN13 |
| Application: | Flow cytometry, Immunohistochemistry, Immunoprecipitation |
| Regulatory Status: | RUO |
| Target Species: | Human | Quantity: | 0.1 mg |
PE
CyFlow™ CD1c PE
| Antigen: | CD1c |
| Clone: | L161 |
| Application: | Flow cytometry |
| Regulatory Status: | RUO |
| Target Species: | Human | Quantity: | 100 tests |
Purified
CyFlow™ CD1c Purified
| Antigen: | CD1c |
| Clone: | L161 |
| Application: | Flow cytometry, Immunohistochemistry, Immunoprecipitation |
| Regulatory Status: | RUO |
| Target Species: | Human | Quantity: | 0.1 mg |