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CyFlow™ CD154 PE
Application: | Flow cytometry |
Isotype: | IgG1 |
Alternative Name: | CD40L, gp39, IMD3, T-BAM, TNFSF5, TRAP-1 |
Antigen: | CD154 |
Target Species: | Human, Non-Human Primates |
Emission Maximum: | 576 nm |
Clonality: | monoclonal |
Excitation Maximum: | 496 nm, 565 nm |
Laser: | Blue, Green, Yellow |
Format/Fluorochrome: | PE |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Clone: | 24-31 |
Order number: | AG649313 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Human CD154 fusion protein Background... more
Product information "CyFlow™ CD154 PE"
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Human CD154 fusion protein |
Background Information | CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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