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CyFlow™ CD158d APC
Application: | Flow cytometry |
Isotype: | IgG1 |
Alternative Name: | 15.212, 103AS, KIR2DL4, KIR103, KIR103AS |
Antigen: | CD158d |
Emission Maximum: | 660 nm |
Clonality: | monoclonal |
Excitation Maximum: | 650 nm |
Laser: | Red |
Format/Fluorochrome: | APC |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | mAb#33 |
Order number: | BN814356 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen NK3.3 cells and KIR2DL4-Ig fusion protein... more
Product information "CyFlow™ CD158d APC"
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | NK3.3 cells and KIR2DL4-Ig fusion protein |
Background Information | CD158d (KIR2DL4) is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-γ secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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