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CyFlow™ CD178 Purified

Application:	Flow cytometry, Functional assays, Immunocytochemistry, Immunoprecipitation, Western blot
Field of Interest:	Apoptosis, Immunophenotyping
Alternative Name:	APO-1L, APT1LG, CD95-L, CD95L, Fas-L, FAS-Ligand, TNFSF6 ligand
Antigen:	CD178
Clonality:	monoclonal
Isotype:	IgG1
Format/Fluorochrome:	Purified
Source Species:	Mouse
Regulatory Status:	RUO
Target Species:	Human
Clone:	NOK-1
Order number:	AS573970

Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more

Product information "CyFlow™ CD178 Purified"

Concentration Unit	mg/mL
Concentration	1
Quantity	0.1 mg
Volume	0.1 mL
Immunogen	L5178Y mouse T lymphoma cells expressing recombinant human CD178
Background Information	CD178 (Fas-L; Fas ligand or CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor Fas/CD95. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
Storage	Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability	Do not use after expiration date stamped on vial label.

Safety Data Sheet

Technical Data Sheet

CyFlow CD178 Purified (NOK-1) AS573970 TDS RUO.pdf

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