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CyFlow™ CD193 APC
Application: | Flow cytometry |
Excitation Maximum: | 650 nm |
Alternative Name: | CC-CKR3, CCR3, CKR3, CMKBR3 |
Antigen: | CD193 |
Emission Maximum: | 660 nm |
Laser: | Red |
Clonality: | monoclonal |
Format/Fluorochrome: | APC |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Isotype: | IgG2b |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | 5E8 |
Order number: | BB919877 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Not available Background Information... more
Product information "CyFlow™ CD193 APC"
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Not available |
Background Information | CD193 (CCR3) is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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