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CyFlow™ CD193 Purified

CyFlow™ CD193 Purified
Application: Flow cytometry
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Isotype: IgG2b
Source Species: Mouse
Field of Interest: Immunophenotyping
Format/Fluorochrome: Purified
Antigen: CD193
Alternative Name: CC-CKR3, CCR3, CKR3, CMKBR3
Clone: 5E8
Order number: AY547099
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD193 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenNot available
Background InformationCD193 (CCR3) is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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