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CyFlow™ CD195 APC

CyFlow™ CD195 APC
Application: Flow cytometry
Isotype: IgG1
Alternative Name: CC-CKR5, CCR5, CKR5, CMKBR5
Antigen: CD195
Field of Interest: Immunophenotyping, Signaling
Emission Maximum: 660 nm
Clonality: monoclonal
Excitation Maximum: 650 nm
Laser: Red
Format/Fluorochrome: APC
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clone: T21/8
Order number: BN959171
Quantity 100 tests Volume 1.0 mL Immunogen CCR5 peptide (Met1-Lys22) KLH conjugate... more
Product information "CyFlow™ CD195 APC"
Quantity100 tests
Volume1.0 mL
ImmunogenCCR5 peptide (Met1-Lys22) KLH conjugate
Background InformationCD195 (CCR5, CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues), such as MIP-1 α, MIP-1 β, or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype, monocytes, macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly, along with CD4, CD195 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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