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CyFlow™ CD205 PE
Application: | Flow cytometry |
Excitation Maximum: | 496 nm, 565 nm |
Alternative Name: | CLEC13B, DEC-205, GP200-MR6, lymphocyte Ag 75 |
Antigen: | CD205 |
Isotype: | IgG1 |
Emission Maximum: | 576 nm |
Laser: | Blue, Green, Yellow |
Clonality: | monoclonal |
Format/Fluorochrome: | PE |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | HD30 |
Order number: | AB042675 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Recombinant Fc-tagged human CD205... more
Product information "CyFlow™ CD205 PE"
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Recombinant Fc-tagged human CD205 |
Background Information | CD205 (DEC-205) is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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