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CyFlow™ CD253 PE

CyFlow™ CD253 PE
Application: Flow cytometry
Emission Maximum: 576 nm
Alternative Name: Apo-2L, Apo2L, TNF-Related Apoptosis Inducing Ligand, TNFSF10, TRAIL
Antigen: CD253
Field of Interest: Apoptosis, Immunophenotyping
Isotype: IgG1
Excitation Maximum: 496 nm, 565 nm
Clonality: monoclonal
Laser: Blue, Green, Yellow
Format/Fluorochrome: PE
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clone: 2E5
Order number: AY917046
Concentration Unit mg/mL Concentration 0,1 Quantity 0.1 mg Volume 1.0 mL... more
Product information "CyFlow™ CD253 PE"
Concentration Unitmg/mL
Concentration0,1
Quantity0.1 mg
Volume1.0 mL
ImmunogenRecombinant soluble fragment (aa 95-281) of human TRAIL
Background InformationCD253 (TRAIL; TNF-Related Apoptosis Inducing Ligand or Apo2) is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).
UsageThe reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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