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CyFlow™ CD255 PE

CyFlow™ CD255 PE
Application: Flow cytometry
Laser: Blue, Green, Yellow
Alternative Name: TWEAK
Antigen: CD255
Field of Interest: Apoptosis, Immunophenotyping
Isotype: IgG3
Emission Maximum: 576 nm
Excitation Maximum: 496 nm, 565 nm
Clonality: monoclonal
Format/Fluorochrome: PE
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clone: CARL-1
Order number: AS153004
Quantity 100 tests Volume 1.0 mL Immunogen Human CD255-transfected 2PK-3 cells... more
Product information "CyFlow™ CD255 PE"
Quantity100 tests
Volume1.0 mL
ImmunogenHuman CD255-transfected 2PK-3 cells
Background InformationCD255 (TWEAK; TNF-related weak inducer of apoptosis), a type II transmembrane protein expressed as membrane-bound and secreted form, can induce apoptosis in many tissues and cell lines through its receptor CD266 (TWEAK R). On the other hand, in endothelial cells this interaction can induce proliferation and promote angiogenesis including neovascularization of tumors. CD255 can act in a juxtacrine manner to initiate cellular responses, and induces secretion of pro-inflammatory cytokines. Besides CD266, CD255 may also bind to DR3.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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