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CyFlow™ CD266 Low Endotoxin

Application:	Flow cytometry, Functional assays, Immunohistochemistry (frozen sections), Western blot
Alternative Name:	Fn14, TNFRSF12A, TWEAK R
Antigen:	CD266
Field of Interest:	Apoptosis, Immunophenotyping
Target Species:	Human, Mouse
Clonality:	monoclonal
Format/Fluorochrome:	Low Endotoxin
Source Species:	Mouse
Isotype:	IgG2b
Regulatory Status:	RUO
Clone:	ITEM-4
Order number:	CQ199952

Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more

Product information "CyFlow™ CD266 Low Endotoxin"

Concentration Unit	mg/mL
Concentration	1
Quantity	0.1 mg
Volume	0.1 mL
Immunogen	Human CD266-transfected P815 cells
Background Information	CD266 (TWEAK R, TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14), is a receptor for CD255 (TWEAK), the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
Storage Buffer	The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Storage	Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability	Do not use after expiration date stamped on vial label.

Safety Data Sheet

Technical Data Sheet

CyFlow CD266 Low Endotoxin (ITEM-4) CQ199952 TDS RUO.pdf

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