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CyFlow™ CD271 APC

CyFlow™ CD271 APC
Application: Flow cytometry
Target Species: Cat, Ferret, Human, Non-Human Primates, Rabbit
Clone: NGFR5
Alternative Name: LNGFR, NGFr(p75), NTR, p75(NTR), TNFRSF16
Antigen: CD271
Clonality: monoclonal
Isotype: IgG1
Emission Maximum: 660 nm
Excitation Maximum: 650 nm
Laser: Red
Format/Fluorochrome: APC
Field of Interest: Immunophenotyping, Neurobiology
Source Species: Mouse
Regulatory Status: RUO
Order number: CW292142
Quantity 100 tests Volume 1.0 mL Immunogen Purified CD271 protein isolated from human... more
Product information "CyFlow™ CD271 APC"
Quantity100 tests
Volume1.0 mL
ImmunogenPurified CD271 protein isolated from human melanoma cell line A875
Background InformationCD271 (NGFR, p75NGFR, p75NTR) is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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