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CyFlow™ HLA-DR1 (empty) PE

CyFlow™ HLA-DR1 (empty) PE
Application: Flow cytometry
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Isotype: IgG2b
Laser: Blue, Green, Yellow
Source Species: Mouse
Format/Fluorochrome: PE
Excitation Maximum: 496 nm, 565 nm
Emission Maximum: 576 nm
Field of Interest: MHC
Antigen: HLA-DR1 (empty)
Clone: MEM-267
Order number: CM093224
Concentration Unit mg/mL Concentration 0,1 Quantity 0.1 mg Volume 1.0 mL... more
Product information "CyFlow™ HLA-DR1 (empty) PE"
Concentration Unitmg/mL
Concentration0,1
Quantity0.1 mg
Volume1.0 mL
ImmunogenPurified, insoluble DR1 β chain (DRB1*0101) expressed in E. coli inclusion bodies
Background InformationHLA-DR1 belongs to the HLA class II β chain paralogues. The MHC Class II molecule is a heterodimer consisting of an α (DRA) and a β chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The β chain is approximately 26-28 kDa. Within the DR molecule the β chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.
UsageThe reagent is designed for Flow Cytometry analysis. Suggested working usage is 5·µg/ml. Indicated dilution is recommended starting point for use of this product, but working concentrations should be validated by the investigator.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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