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CyFlow™ PCLO PE
Application: | Flow cytometry |
Clonality: | monoclonal |
Target Species: | Human |
Regulatory Status: | RUO |
Laser: | Blue, Green, Yellow |
Source Species: | Mouse |
Format/Fluorochrome: | PE |
Excitation Maximum: | 496 nm, 565 nm |
Emission Maximum: | 576 nm |
Isotype: | IgG1 |
Field of Interest: | Adaptor proteins, Neurobiology |
Antigen: | PCLO |
Clone: | PCLO-01 |
Order number: | BR521844 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 0,1 Quantity 0.1 mg Volume 1.0 mL... more
Product information "CyFlow™ PCLO PE"
Concentration Unit | mg/mL |
Concentration | 0,1 |
Quantity | 0.1 mg |
Volume | 1.0 mL |
Immunogen | Human recombinant PCLO protein |
Background Information | PCLO (piccolo, aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion. |
Usage | The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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