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CyFlow™ CD3 PerCP
Application: | Flow cytometry |
Clonality: | monoclonal |
Target Species: | Human |
Regulatory Status: | RUO |
Laser: | Blue, Green |
Source Species: | Mouse |
Field of Interest: | Immunophenotyping |
Antigen: | CD3 |
Alternative Name: | Leu4, T3 |
Clone: | MEM-57 |
Isotype: | IgG2a |
Format/Fluorochrome: | PerCP |
Excitation Maximum: | 482 to 490 nm |
Emission Maximum: | 678 nm |
Order number: | BA290102 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA IV—WS Code T 96 Quantity 100 tests Volume 1.0 mL Immunogen... more
Product information "CyFlow™ CD3 PerCP"
HLDA Workshop | HLDA IV—WS Code T 96 |
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Human thymocytes and T lymphocytes |
Background Information | CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3γ, CD3 δ, CD3ε and CD3ζ. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow CD3 PerCP (145-2C11) BS047660 TDS RUO.pdf
- CyFlow CD3 PerCP (MEM-57) BA290102 TDS RUO.pdf
- CyFlow CD3 PerCP (UCHT1) BW363553 TDS RUO.pdf
- CyFlow CD3 PerCP-Cy5.5 (145-2C11) BJ628650 TDS RUO.pdf
- CyFlow CD3 PerCP-Cy5.5 (SK7) AV981175 TDS RUO.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) CL350220 TDS RUO.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) AS531857 TDS ASR EN.pdf
Certificate Of Analysis
- CyFlow CD3 PerCP-Cy5.5 AS531857 COA 902808.pdf
- CyFlow CD3 PerCP-Cy5.5_AS531857_COA_901792.pdf
- CyFlow CD3 PerCP-Cy5.5 AS531857 COA 903676.pdf
- CyFlow CD3 PerCP-Cy5.5 BV189571 COA 904580.pdf
- CyFlow CD3 PerCP-Cy5.5 AS531857 COA 904580.pdf
- CyFlow CD3 PerCP-Cy5.5 AS531857 COA 905778.pdf
- CyFlow CD3 PerCP-Cy5.5 BV189571 COA 905778.pdf
- CyFlow CD3 PerCP-Cy5.5 AS531857 COA 907423.pdf
- CyFlow CD3 PerCP-Cy5.5 BV189571 COA 907423.pdf
- CyFlow CD3 PerCP-Cy5.5 AS531857 COA 908179.pdf
- CyFlow CD3 PerCP-Cy5.5 AS531857 COA 909240.pdf
ECDoC
Instruction for Use
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU CZ CZ.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU DE DE.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU DK DK.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU ES ES.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU FR FR.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU GR EL.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU IT IT.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU NL NL.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU NO NO.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU PL PL.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU PT PT.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU RU RU.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU SE SV.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU SK SK.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU TR TR.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU GB EN.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU BG BG.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU HR HR.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU RO RO.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU SI SL.pdf
- CyFlow CD3 PerCP-Cy5.5 (UCHT1) BV189571 IFU RS SR.pdf
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