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CyFlow™ CD8 PE-Cy5
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Target Species: | Human |
| Regulatory Status: | RUO |
| Laser: | Blue, Green, Yellow |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping |
| Excitation Maximum: | 496 nm, 565 nm |
| Isotype: | IgG2a |
| Format/Fluorochrome: | PE-Cy5 |
| Emission Maximum: | 670 nm |
| Antigen: | CD8 |
| Clone: | MEM-31 |
| Order number: | CH689927 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA III—WS Code T 575 Quantity 100 tests Volume 0.4 mL Immunogen... more
Product information "CyFlow™ CD8 PE-Cy5"
| HLDA Workshop | HLDA III—WS Code T 575 |
| Quantity | 100 tests |
| Volume | 0.4 mL |
| Immunogen | Crude thymus membrane fraction |
| Background Information | The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as α/β heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as α/α homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8 β level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 α-β but not α-α dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow CD8 PE-Cy5 (MEM-31) CH689927 TDS RUO.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CZ173018 TDS ASR EN.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CZ173018 TDS ASR EN.pdf
Certificate Of Analysis
- CyFlow CD8 PE-Cy5 CZ173018 COA 903019.pdf
- CyFlow CD8 PE-Cy5 CC139069 COA 904529.pdf
- CyFlow CD8 PE-Cy5 CZ173018 COA 904529.pdf
- CyFlow CD8 PE-Cy5 CZ173018 COA 906703.pdf
- CyFlow CD8 PE-Cy5 CC139069 COA 906703.pdf
ECDoC
Instruction for Use
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU IT IT.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU NL NL.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU NO NO.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU PL PL.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU PT PT.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU RU RU.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU SE SV.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU SK SK.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU TR TR.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU CZ CZ.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU DE DE.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU DK DK.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU ES ES.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU FR FR.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU GR EL.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU BG BG.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU HR HR.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU RO RO.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU SI SL.pdf
- CyFlow CD8 PE-Cy5 (MEM-31) CC139069 IFU RS SR.pdf
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