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CyFlow™ CD11c Pacific Blue™

CyFlow™ CD11c Pacific Blue™
Application: Flow cytometry
Clonality: monoclonal
Target Species: Human, Non-Human Primates
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping
Isotype: IgG1
Format/Fluorochrome: Pacific Blue™
Laser: Violet
Excitation Maximum: 400 to 410 nm
Emission Maximum: 455 nm
Antigen: CD11c
Alternative Name: p150
Clone: BU15
Order number: AP415041
HLDA Workshop HLDA III—WS Code M 256 HLDA V—WS Code AS S143 HLDA VI—WS Code AS Ref.6... more
Product information "CyFlow™ CD11c Pacific Blue™"
HLDA WorkshopHLDA III—WS Code M 256 HLDA V—WS Code AS S143 HLDA VI—WS Code AS Ref.6
Quantity100 tests
Volume0.4 mL
ImmunogenDendritic cells of synovial fluid
Background InformationCD11c (αX integrin subunit) forms complex with CD18 (β2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other β2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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